ecancermedicalscience

Short Communication

Prevalence of human papillomavirus types in head and neck cancer sub-sites in the Indian population

17 Feb 2022
Devyani Gholap, Sharayu Mhatre, Pankaj Chaturvedi, Sudhir Nair, Tarik Gheit, Massimo Tommasino, Rajesh Dikshit

Although a subset of head and neck cancers (HNC) has been associated worldwide with mucosal high-risk human papillomaviruses (HPV), information on the prevalence of HPV-positive HNC in India is limited. In this study, we examined the prevalence of 21 subtypes of HPV in sub-sites of HNC (n = 175) in the western region of India. Type-specific multiplex genotyping assay was conducted at the Centre for Cancer Epidemiology, Tata Memorial Centre, to determine the prevalence of HPV subtypes. The HPV prevalence was observed to be 28.43%, 41.67%, 38.89% and 15.79% in the oral cavity, oropharynx, hypopharynx and larynx tumour tissues, respectively. The HPV 16 genotype was most common in all HNC tumour tissues (30.29%), followed by HPV 58 (0.57%).

Related Articles

Zuzaki Shabin, Rejnish Kumar, Malu Rafi, Lekha M Nair, Krishnapriya Pisharody, Nijo Jose, Indu Sasikumar, John Mathew, Kumara Pillai Mohanan Nair, Kainickal Cessal Thommachan
Ranti Ghosh, Debarshi Lahiri, Debjit Ghosh, Kushal Sen, Debanjan Chakraborty, Tapas Maji, Suparna Mazumder, Ranajit Mandal, Arit Bhattacharjee, Jayanta Chakrabarti
Anass Baladi, Hassan Abdelilah Tafenzi, Fatim-Zahra Megzar, Ibrahima Kalil Cisse, Othmane Zouiten, Leila Afani, Ismail Essaadi, Mohammed El Fadli, Rhizlane Belbaraka