ecancermedicalscience

Case Report

Slowly developing toxic epidermal necrolysis-like reaction associated with pemetrexed and carboplatin

13 Feb 2020
Gerhard Eichhoff

Most cutaneous adverse drug reactions reported in association with chemotherapy, such as a limited maculopapular rash, are considered mild and do not affect the continuation of the treatment. Toxic epidermal necrolysis (TEN), however, is a life-threatening reaction that needs treatment discontinuation. The present case shows the slow progression from a pemetrexed and carboplatin-associated maculopapular rash to a TEN-like reaction.

Related Articles

Berthe Sabine Esson Mapoko, Etienne Atenguena, Abdel Nasser Nsangou Moun, Esther Dina Bell, Lionel Tabola, Dominique Anaba, Anne Sango, Rachel Tayou
Liudmila Castelo David, Teresa Mota Garcia, Isaulina Barreto, Esperança Carvalho, Laurinda Barreto, Clara Aleydis, Laurinda Coelho, Lúcio Lara Santos
Sree Siva Kumar Raja Addagalla, Vanita Noronha, Nandini Menon, Minit Shah, Amit Joshi, Anokhi Shah, Kumar Prabhash
Charles M Balch, Ning Liao, Dennis S C Lam, Jeffrey N Weitzel, Rui-Hua Xu, Gerhardt Attard, Paul A Bunn, Alexander M M Eggermont, Jie He, Yuko Kitagawa, Soon Thye Lim, Eduardo Cazap, Bernard Esquivel, Xianqun Fan, Louis W C Chow, Edward S F Liu, Hector Martinez Said, John E Niederhuber, Isabel T Rubio, Ashraf Saad Zaghloul, Oscar G Arrieta, Riccardo A Audisio, Geerard L Beets, Felipe J F Coimbra, Jorge E Gallardo, Judy E Garber, Alessandro Gronchi, Volker Heinemann, Allison W Kurian, Miriam Mutebi, Masaki Mori, Funmi I Olopade, Piotr Rutkowski, Mansoor Saleh, William M Sanchez, Raymond Sawaya, John F Thompson, Gerald Tumusiime, Carlos S Vallejos, David C Whiteman, YiLong Wu, King-David T Yawe, Nayef Awad Al Zahrani, Odysseas Zoras, Banu K Arun, Carol J Fabian, Jeffrey E Gershenwald, William J Gradishar, Jin He, V Suzanne Kimberg, Ronald M K Lam, Victor H F Lee, Domenica Lorusso, Tony S K Mok, N D Perrier, Hope S Rugo, Cornelia Ulrich, Chandrakanth Are, J Vignat, I Soerjomataram