Health problems in the Latin American and Caribbean (LAC) region are mainly associated with noncommunicable diseases, with cardiovascular disease and cancer being the leading causes of death. However, knowledge and training opportunities in cardio-oncology, as well as active cardio-oncology groups, are mainly limited to large academic institutions or isolated private groups. To contribute to the implementation of viable strategies to ensure equitable access to care for all, it is essential to understand the current situation. This publication assesses the epidemiological situation of cancer in LAC and discusses the development of cardio-oncology in the region. It analyses the results of the survey on knowledge and medical action in cardio-oncology carried out among a group of physicians involved in the care of oncology patients and proposes recommendations based on the results obtained.