Enzalutamide plus radium-223 extends survival in bone metastatic prostate cancer

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Published: 18 Mar 2026
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Dr Enrique Gallardo - Parc Taulí University Hospital, Sabadell, Spain

Dr Enrique Gallardo speaks to ecancer about final overall survival results from the EORTC 1333/PEACE-3 trial.

He discusses the trial results which showed that combining enzalutamide with radium-223 significantly prolongs overall survival in men with bone-dominant metastatic castration-resistant prostate cancer.

The combination also improves radiological progression-free survival, with a safety profile similar to enzalutamide alone.

Dr Gallardo breaks down how this therapy works, the key outcomes, and what it means for patients with advanced prostate cancer.

ecancer's filming has been kindly supported by Amgen through the ecancer Global Foundation. ecancer is editorially independent and there is no influence over content.