Prof Richard Sullivan reflects on the findings of the Lancet Oncology Commission on the Human Crisis of Cancer, which examines fundamental weaknesses in global cancer control. He discusses how advances in cancer drugs and technologies have increasingly overshadowed the human dimensions of cancer, including patient experience, psychosocial support, palliative care, and the impact on families.

Prof Sullivan highlights failures in health system reform and the limited implementation of national cancer control plans, alongside the growing financial burden faced by patients and households. He emphasises the role of economics, macroeconomic pressures, and political choices in shaping cancer care, particularly in low-resource and conflict-affected settings.

Focusing on Africa, he outlines how fragility, conflict, and constrained funding are placing severe strain on cancer systems, while also highlighting the importance of context-specific programmes, international collaboration, and solidarity to support sustainable, compassionate cancer care.