Dr Enrique Velazquez Villarreal speaks to ecancer about multi-omics analysis of MYC gene and WNT signalling pathway alterations in early-onset colorectal cancer in Hispanic/Latino patients, enhanced with spatial transcriptomics approaches.
This study investigates colorectal cancer within Latino populations by analysing genomic data and mutation differences.
It highlights high incidence rates and characterises tumours based on onset age.
Ancestry analysis links super populations to cancer incidence, while gene frequency findings show variations from global studies.
Spatial transcriptomics uncovers interactions between cancer and immune cells, and an AI tool is developed to enhance data analysis for improved treatment strategies.