High-fibre dietary intervention in precursor plasma cell disorders improves biomarkers of disease, may delay progression to myeloma

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Published: 9 Jan 2025
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Dr Urvi Shah - Memorial Sloan Kettering Cancer Center, New York, USA

Dr Urvi Shah speaks to ecancer about her study presented at ASH 2024.

This study investigates a high-fibre dietary intervention for patients with monoclonal gammopathy of undetermined significance and smouldering myeloma, aiming to delay disease progression.

Involving 20 patients, the pilot study achieves a 7-8% weight loss and maintains dietary adherence for over a year.

Biomarker analysis shows metabolic improvements and positive immune function changes.

Future research plans to expand the study to over 150 patients to explore dietary supplements' effects.